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Package cost

IVF €4300

Egg donation €3750

Basic information about IVF treatment at S.I.S.Me.R..

Maximum age of the woman: 50
Single woman: not allowed
Lesbian couples: not allowed
HIV positive patients: not allowed
HCV/HBV positive patients: allowed
HCV/HBV positive patients: allowed

S.I.S.Me.R. clinic was established in 1994 and employs professionalists who were previously operating at a different clinic since 1985. In 2019, the clinic performed in total 716 treatments of which 11.9% were egg donation cycles, 74.2% were IVF cycles with own eggs (this includes all techniques: IVF/ICSI, PGT, frozen embryo replacements, and social freezing) and 13.9% were IUI treatments and initiated cycles.

The clinic is located in an own 4-floor building with an operating theatre, embryology lab, and the ward on the ground floor, 5 consultation rooms on the first floor, an andrology lab, molecular biology lab, and administrative offices on the second floor and a meeting room (capacity for up to 60 people) on the third floor.

There are 3 laboratories, one operating theatre (picture below), and 2 recovery rooms for patients (one with 2 beds ensuite, and one with 6 beds + bathroom).

SISMER operating theatre

The Medical Director is Dr. Daniele Barnabè who has a University Degree in Medicine and Surgery (1980, Bologna University) and is Specialized in Obstetrics and Gynecology (1984, Bologna University) and has Expertise in Quality Management. The Scientific Director is Dr. Luca Gianaroli, whose professional expertise in the field of Medically Assisted Reproduction is acknowledged nationally and internationally. He is a pioneer of PGT and a Past Chairman of the European Society of Human Reproduction and Embryology.

At the clinic, there are five doctors (excluding the Medical Director) and eight embryologists/biologists, one with 30 years of experience. The laboratory director, Dr. Maria Cristina Magli is an ESHRE Certified Senior Embryologist and the current chairman of ESHRE. All staff speaks English fluently.

S.I.S.Me.R. holds ISO 9001:2015 and has been certified since 1998 and is the first certified IVF Centre in Italy. It is also a Licensed Center in compliance with the Italian legislation.

S.I.S.Me.R. Fertility Treatments

  • Egg donation
  • Donor sperm
  • PGT
  • Assisted Hatching
  • Embryo/egg/sperm freezing
  • Blastocoel fluid biopsy for PGT

To learn more about PGT and personalized IVF, watch the #IVFWEBINARS with dr. Luca Gianaroli from S.I.S.Me.R. – “Preimplantation genetic testing (PGT) – for whom and how does it help?” and “Personalization of (IVF) ART treatments“.

Need to find out more about a particular treatment? Contact S.I.S.Me.R.

S.I.S.Me.R. Price List 2019

IVF with own eggs

The cost of an IVF with own eggs program is €4,300 and it includes:

  • hormonal assays,
  • ultrasound monitoring,
  • oocyte retrieval,
  • in vitro fertilization,
  • embryo culture,
  • embryo transfer,
  • cryopreservation of surplus embryos.

Egg Donation Program

Depending on the egg donation program selected by the couple, the price ranges between €3,750-6,900. The programs include:

  • egg donor selection and treatment,
  • matching,
  • psychological consultation,
  • oocyte insemination,
  • ICSI,
  • extended culture to blastocyst,
  • embryo/egg vitrification,
  • one embryo transfer.

The cost of the first consultation is €202 and it can be done in person or by video call. The cost of sperm freezing is €302 + a subsequent yearly fee for storage. The clinic offers an egg sharing program as well.

If you decide to go back to the clinic for a frozen embryo transfer, the cost is €1,800.

Use our IVF Cost Calculator to help understand costs.

If you have any questions about treatments, Contact S.I.S.Me.R.

S.I.S.Me.R. Success Rates 2019

The egg donation clinical pregnancy rate per embryo transfer was 40.8%.

The clinical pregnancy success rate for IVF with own eggs per embryo transfer in 2019 was 21% and the success rates per age were as follows:

  • women under 35 years old: 35%
  • women 35-40 years old: 25%
  • women over 40 years old: 8%

The frozen embryo clinical pregnancy success rates were 26%.

At S.I.S.Me.R., the doctors transfer an embryo on day 3 or day 5 or other depending on the type of treatment performed. Only one embryo is usually transferred (2 embryos are transferred rarely and in specific cases). This gave the multiple birth rate of 2.5% in 2018.

Need more information on IVF success rates? Contact S.I.S.Me.R.


From the staff

At SISMER we care about our patients, accompanying them during their diagnostic and therapeutic pathway and offering them top quality Reproductive Care since 1994. SISMER offers all ART treatments allowed in Italy at its headquarters in Bologna and at its associated Centers in Italy and Switzerland. A multidisciplinary team of professionals is at patients’ disposal throughout their whole journey.

SISMER cares about safety and quality. It is an ISO certified Center since 1998 and gives great importance to research and education.

SISMER Reproductive Care. A matter of Health. And Life.

Who attends?

The patients of the clinic are mostly Italian (97%), the others come from Hungary, Switzerland, the USA, the UK, the UAE (2%) and 1% comes from Malta.

Clinic Location

S.I.S.Me.R. is located within walking distance from the city centre of Bologna. From the railway station: approx. 25 min. (bus stop right outside the clinic – lines 25, 27, 32, 33), by taxi from the railway station: approx. 10 minutes. By taxi from the airport: approx. 40 min (except rush hours). There is no private parking, several car parks are available nearby. Discounted rates for S.I.S.Me.R.’s patients.

For patients and guests, S.I.S.Me.R. has made agreements with a group of selected hotels. The affiliated 4-star hotels include Grand Hotel Majestic (già Baglioni), Hotel Aemilia, Hotel Commercianti Novecento, Al Cappello Rosso, Al Cappello Rosso, Al Cappello Rosso, Hotel I Portici, Tower Hotel Bologna Best Western Plus, Hotel Corona d’Oro, Savhotel, and 3-star hotels are Blumen, Orologio and Metropolitan.

Center map
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By Dorothy Walas

Basic information about treatment restrictions at S.I.S.Me.R..

Maximum age of the woman:50
Single woman: not allowed
Lesbian couples: not allowed
HIV positive patients: not allowed
HCV/HBV positive patients: allowed

Use the form below to contact S.I.S.Me.R. if you need some more information on IVF costs, success rates, clinic experience or anything else. There's no commitment.

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