Clínica Tambre is a pioneering medical-surgical centre specialised in gynaecology and fertility located in two Spanish cities: Madrid and Alicante. It was founded in 1978 and is a private clinic. In 2017 it carried out about 1000 treatment cycles. Its mission is to help patients fulfil their dream of giving birth to a healthy baby, and contribute to the development of science, medicine and society.
The former president, Dr. Pedro Caballero, started his career in assisted reproduction over 40 years ago, which makes Clínica Tambre Madrid’s most-experienced medical centre in the field of fertility. With more than 56 published scientific studies, Caballero is considered a strong reference among the scientific community.

Clinica Tambre in Alicante
Furthermore, Dr. Pedro Caballero used his experience in andrology to create the second Spanish semen bank in 1980. His entire team shares his ambition, commitment and dedication, this allows Clínica Tambre to position itself as a top-level clinic within and outside of Spain. However, the key to Caballero’s success is not only due to his 40 years of experience and entrepreneurial spirit. Clínica Tambre also stands out in offering patients warm and personalised care, success rates well above the Spanish and European average, an excellent medical team and the deployment of the most accurate and recent technology.
Clínica Tambre was completely renovated in 2018, the year in which Inge Kormelink took charge of Tambre. There are two laboratories; one destined for IVF and the other for andrology. After treatment, patients can enjoy the comfort of private recovery rooms, of which there are 6.
Interested in this clinic? Contact Clinica Tambre
We would like to thank Dr. Marban for all her wisdom, support and help throughout the process and especially Anabel for accompanying us unconditionally, holding our hand and never letting go, making the difficult and complicated moments more bearable.
We are super happy, and above all satisfied, to have placed our trust in Tambre, without a doubt it was our best success from which we already have our greatest gift in life.
We invite couples or people who are looking for a clinic to choose Tambre because I assure you that you will not regret it. We would choose them a thousand times.... ❤️
Unfortunately we had 3 other clinics let us down for years , wasting our time , mentally and physically not to mention financially, we nearly gave up after 3 long years, until we came across tambre and all it’s great reviews, we researched this clinic well and thought let’s give it one more go and we are so glad we did!!
The staff are all so friendly and make you feel updates, heard and comfortable.
First time ever we are now 10 weeks pregnant with healthy heartbeat , it’s still early days but we have never got this far and very hopeful.
Clinica Tambre Alicante
Clinica Tambre now welcomes patients in two locations: their established clinic in Madrid, in the quiet El Viso neighbourhood, and their new clinic in Alicante, facing the port and the sea. Tambre Alicante has been created as a modern fertility clinic with a strong focus on medical care, privacy and patient comfort during treatment.
The opening of Tambre Alicante allows the clinic to bring their long-standing experience in reproductive medicine to the Costa Blanca. For over 48 years, the Tambre team has supported women and couples on their path to parenthood. Their approach is based on accurate diagnosis, personalised treatment planning and continuous support throughout the process.
The clinic has been designed to offer a calmer experience for patients. Bright interiors, natural light and individual waiting areas help create a more private and comfortable setting, especially during consultations and important medical conversations.
As Inge Kormelink explains, “every patient is unique, every body is different, and at Tambre we understand that.”
This idea is reflected in the way their team listens to each patient’s story and adapts care to their individual needs.

Clinica Tambre in Alicante
At Tambre Alicante, patients have access to modern facilities, advanced laboratory technology and a medical team experienced in assisted reproduction. The clinic combines reproductive medicine, technology and personalised care from the first consultation through diagnosis and treatment.
Clinica Tambre also supports international patients travelling to Spain for fertility treatment. Their doctors, fertility consultants and coordinators speak English, French, German, Italian, Dutch and Spanish. International patients are guided from the first appointment onwards, with support in their own language at different stages of the fertility journey.
Medical Team at Clinica Tambre
Tambre’s team has broad experience, led by medical director Dr Laura Garcia de Miguel, who is a specialist in obstetrics and gynaecology with a master’s degree in human reproduction. The entire team comprises 8 fertility specialists, 7 embryologists (the senior embryologist is ESHRE accredited) and 6 nurses. The international team consists of cross-cultural experts who facilitate communication from the first contact to the end of the treatment. The team speaks several languages, including English, Italian, German, Dutch, French and of course, Spanish.

Dr Laura Garcia de Miguel
Dr Esther Marbán Bermejo is an experienced gynecologist and fertility specialist with 14 years of experience. Fluent in Spanish and English, she is committed to delivering exceptional care and support to her patients.

Dr Esther Marbán Bermejo
Tambre Team Shares Their Expertise with Patients
The specialists at Clínica Tambre have presented insightful webinars on key fertility topics to support patients in making informed decisions. Below are links to their sessions on MyIVFanswers.com, offering valuable knowledge and expert guidance.
- “Egg Quality & IVF Success: How Age Makes a Difference” — a webinar led by Dr. Marina Díaz, Gynaecologist & Fertility Specialist at Clínica Tambre, exploring how age influences egg quality and IVF outcomes, with practical tips to enhance fertility potential and informed decision-making.
- IVF Life Stories with Inge Kormelink – Professionals reflect on their own pathway to parenthood – an inspiring conversation with Inge Kormelink, CEO of Clínica Tambre who shared her incredible journey—from overcoming personal fertility challenges to leading one of Europe’s top fertility clinics.
- “IVF & Fertility Treatment for Women Over 40 – What Are Your Chances?” — a webinar with dr Esther Marbán.
- “Understanding and overcoming IVF failure: causes, strategies, and new insights” — a webinar with dr Esther Marbán.
- “Recurrent Pregnancy Loss (RPL): understanding the causes and exploring solutions” — a webinar with dr Abraham Zavala.
- “Embryo grading explained: The Good, The Bad, The Baby Maker” — a webinar with Carolina Andrés, Senior Embryologist.
- “Weight and Fertility: does BMI really matter?” — a webinar with dr Abraham Zavala.
- “AMH levels and their impact on fertility” — a webinar with dr Abraham Zavala.
- “Fertility for women over 40: what are my options?” — a webinar with dr Esther Marbán.
These recorded webinars will provide you with valuable knowledge and help you better prepare for your visit to our clinic.
Clínica Tambre has the largest and longest-standing sperm bank in Madrid and provides samples to other clinics all over Spain; the sperm bank is professionalised in both the male and female factor. Clínica Tambre is committed to quality controls. Tambre was the first in Spain to receive ISO accreditations; ISO 9001:2015 as well as ISO 14001 and the Health Ministry regulation UNE 179007. They are the only European clinic to have received the EFQM European Quality Management Finalists Award in 2005 & 2008. Apart from their own bio-sample tracking systems, they have also a system called Witness. It consists of an RF Card (radio frequency card) given to patients which locks the patient’s identity to the sperm, eggs and embryos at every stage of the treatment.
Would you like to hear from this clinic? Contact Clinica Tambre
Clinica Tambre IVF Treatment Options
The following fertility treatments and procedures are available at Clinica Tambre:
- IUI (intrauterine insemination) and AID (artificial insemination with donor)
- IVFwith own eggs
- IVF with ICSI (you may want to read “To ICSI or Not to ICSI: Should ICSI Be Considered in Every IVF Cycle?”)
- Egg donation (own egg bank)
- Sperm donation (own sperm bank)
- Embryo donation
- Fertility Preservation/Social Freezing
- the ROPA method (Reciprocal IVF for same-sex lesbian couples)
- Embryo freezing
- Sperm freezing
Also, diagnostics tests are available:
- CometFertility® is a diagnostic test performed to obtain a diagnosis related to the male factor. This technique analyses the DNA fragmentation that can occur in a sperm sample
- Chromosperm and FISH – these tests allow embryologists from the Andrology Laboratory to evaluate the global chromosome content of the sperm cells in your partner’s sample. This is a fast and effective way of detecting the overall genetic load that could affect the success of your treatment
- KIR and HLA-C Genotyping – dedicated to patients with a history of implantation failure and recurrent miscarriages. It is a study of the compatibility between uterine KIR receptors (killer immunoglobulin-like receptors) and the HLA-C molecules that the embryo will present and that will be recognized by these receptors
- myPrenatal® – is an advanced prenatal screening test, which analyses cell-free foetal DNA and studies the possible existence of chromosomal abnormalities. It detects three of the most frequent trisomies in the foetus: Down syndrome, Edwards syndrome and Patau syndrome, as well as two sex chromosomal alterations: Turner syndrome (45, X) and Klinefelter syndrome (47, XXY).
- PGD (Preimplantation Genetic Diagnosis) is an Assisted Reproduction technique that allows us to study the genetic material of embryos before they are transferred and select the healthiest embryos to ensure that no chromosome or genetic abnormalities are present.
If you are aged 38-50, you might be interested in reading “PGT-A in Patients with Advanced Maternal Age – Success Stories”.
At Clinica Tambre, patients can benefit from the following technologies being applied:
- Embryo monitoring (GERI-incubator) allows monitoring of the embryos through a time-lapse system without extracting them from the medium
- Fenomatch – the latest technique to find an egg or sperm donor who has a similar phenotype to you and your partner
- RI Witness™ – a security system that identifies the semen, egg, and embryo samples of each patient.
If you happen to be diagnosed with an endometrial factor, Clinica Tambre is the right clinic for you. Their specialists deal with endometrial issues and displaced window of implantation. You may want to read “Endometrial Factor and Displaced Window of Implantation | Real Patient Success Stories” where we present two couples with a history of two failed IVF cycles each and, finally diagnosed with displaced window of implantation. Find out how different approach helped them get pregnant.
Endometrial and Ovarian PRP at Tambre
Clinica Tambre also offers PRP treatment with the specific goal of improving endometrial development and thickness in women who have experienced repeated implantation failures or who have been diagnosed with refractory endometrium. This procedure is an in-house service, ensuring that the entire process takes place within the clinic, thereby reducing the waiting time. This approach prioritizes patient comfort throughout the entire journey.
Need to find out more about a particular treatment? Contact Clinica Tambre
Clinica Tambre IVF Costs
IUI (intrauterine insemination) – 1,100 Euros.
- First and subsequent medical consultations
- Monitoring during the cycle
- Andrology laboratory and sperm capacitation
- Artificial insemination.
AID (artificial insemination with donor) – 1,595 Euros. Services included:
- First and subsequent medical consultations
- Monitoring during the cycle
- Sperm bank
- Artificial insemination.
Genetic matching costs 1,295 Euros.
IVF with Own Eggs
The price of IVF treatment using own eggs starts from 4,395 Euros. Included in this price are sedation, ICSI fertiisation technique, Andrology laboratory and sperm capacitation, Double security syste (RI Witness), blastocyst culture and embryo transfer. Embryo freezing of non-transferred embryos: 550 Euros for the first year including storage, sperm freezing is 120 Euros. If you are interested in the best program with own eggs, check this Top IVF Program by Clinica Tambre.
Endometrial Therapy with Platelet-rich Plasma (PRP) costs 900 Euros.
Ovarian PRP (one of the tecniques used for ovarian regeneration costs 1,400 Euros.
IVF with Donor Eggs
The egg donation treatment is 6,500 Euros. Such package includes ICSI, sperm freezing, minimum of 1 Blastocyst embryo guarantee, one embryo transfer, donor´s expenses, using the Double traceability system of samples with RI Witness and a Pregnancy confirmation analysis: bETA-hCG. The first consultation will be deducted from the final cost of the treatment.
The next package with donor eggs costs 8.700 Euros. This includes ICSI, sperm freezing, minimum of two blastocysts embryos guarantee, one embryo transfer, donor´s expenses, using the Double traceability system of samples with RI Witness and a Pregnancy confirmation analysis: bETA-hCG.
Neither of these packages includes freezing of surplus embryos or embryo storage.
ROPA Method at Clinica Tambre
Clinica Tambre welcomes lesbian and transgender couples for ROPA treatment (reciprocal IVF). There are a few packages available:
- ROPA Classic Day 3 – 5,100 Euros.
- ROPA Day 5 Premium – 6,500 Euros.
- ROPA Day 5 Premium + Genetics ( ICSI, PGT-A, Time-lapse GERI® Incubator, RI Witness, Embryo freezing and first year of maintenance included – 8.295 Euros for 1 embryo,9.245 Euros for 2 embryos and 9,995 Euros for 3 embryos to analyse.
- ROPA Cycle Plus (2 cycles and 1 embryo transfer, Embryo freezing and first year of maintenance included ) – 12,100 Euros.
- ROPA Cycle Plus + Genetics (2 cycles + (PGT-A) + Time-lapse GERI® Incubator included) – 15,045 Euros.
If you are looking for embryo adoption, this is also available at Tambre, costs 4,395 Euros and includes any additional ultrasounds and/or hormonal tests needed prior to the embryo transfer.
Fertility Preservation at Clinica Tambre
Are you looking for fertility preservation? At Clinica Tambre, you have a variety of egg freezing options.
- Tempo Package – 1-year storage – 1,995 Euros.
- Tempo Package – 5-year storage – 2,950 Euros.
- Tempo Plus Package (two egg retrievals under sedation) – 1-year storage – 3,495 Euros.
- Tempo Plus Package (two egg retrievals under sedation) – 5-year storage – 4,950 Euros.
A frozen embryo transfer, at Clinica Tambre, is 1,650 Euros. Feel free to use our IVF Cost Calculator to help you understand IVF costs more.
If you have any questions about these packages, contact Clinica Tambre
Clinica Tambre Success Rates
Success rates are good, particularly for egg donation. The egg donation clinical pregnancy success rate of 2018 was 97.6% and IVF clinical rate was 86.9%. In 2018, the IVF with own eggs clinical pregnancy success rates were:
- under 35 years old: 58.6%
- 35-40 years old: 56.7%
- over 40 years old: 34.4% (with PGD 76.2%)
The frozen embryo clinical pregnancy rate was 56% and the embryo donation clinical pregnancy rate was 67.2%. The clinical pregnancy success rate for the ROPA method was 50.14%. Clinica Tambre submits its results to the Spanish Fertility Society (SEF) for verification. The recent success rates for 2020 will be published as soon as SEF audits them. In 2018, the multiple birth rate was 2.1%. The clinic’s preferred day of transfer is day 5 of the blastocyst stage.
Need more information on IVF success rates? Contact Clinica Tambre
From the Staff
We have over 40 years of experience! Our extensive career in the world of reproductive medicine has allowed us to achieve the highest success rates not only in Spain but also throughout Europe. We are pioneers in assisted reproduction and therefore have the most complete, compassionate and experienced team of fertility experts to ensure that you walk out of our clinic with a healthy baby.
Who Attends?
Of the people who attend Clinica Tambre, 50% of the patients are Spanish, 15% come from the UK, 15% are from France, 10% are from Italy and 10% are from other countries. 9 out of 10 women who were treated by the Tambre team in 2017 reached their dream of becoming pregnant.
Clinic Locations
Clinica Tambre has two locations in Spain: Madrid and Alicante.
The Madrid clinic is located on a quiet, high-end residential street in the Chamartín district. It is approximately 11 km from the airport, 1.5 km from the nearest hotel and 4 km from the city centre. The clinic is also a few minutes’ walk from the nearest metro station and around 15 minutes by taxi from the airport. Clinica Tambre may offer a free airport pickup service and has agreements with selected local hotels.
The exact address of Clinica Tambre Madrid is C. del Tambre, 8, Chamartín, 28002 Madrid, Spain. The clinic is open Monday to Friday from 8:00 AM to 8:00 PM, and on Saturdays from 8:00 AM to 2:00 PM. The clinic is closed on Sundays.
Clinica Tambre Alicante is located in Panoramis Life & Business, facing the port and the sea. The exact address is Av. Perfecto Palacio de la Fuente, 6, 03003 Alicante, Spain. Patients can contact the Alicante clinic by phone at +34 965 02 62 74. The Alicante clinic is open Monday to Friday from 8:00 AM to 4:00 PM. It is closed on Saturdays and Sundays.
If you’re considering Spain as your go-to destination for IVF, you may want to read “IVF Treatment in Spain for Patients from the UK.”









